Follicular lymphoma of the duodenum.

common site for the presentation of extranodal non-Hodgkin’s lymphoma. Depending on the series, follicular lymphoma of the gastrointestinal tract accounts for 3.6 % of gastrointestinal lymphoma [1]. Above all, follicular lymphoma shows a predilection for the duodenum, where 55.6 %– 62.5 % of cases are located [1,2]. We present the case of a 47-year-old woman with epigastralgia. An elevated lesion like a flower petal was found at the second portion of the duodenum on panendoscopy (l" Fig. 1). Duodenoscopy showed a whitish lesion surrounding the major duodenal papilla (l" Fig. 2). Although the follicular lymphoma of the small intestine showed multiple whitish lymphomatous polyps [1, 3], ampullary carcinoma could be included in the differential diagnosis. Histopathologic evaluation from biopsy specimens revealed a proliferation of atypical lymphoid cells forming folliclelike structures in the lamina propria of the duodenum (l" Figs. 3 and 4). On immunohistochemical study, the atypical lymphoid cells were diffusely positive for CD20, CD10, and Bcl-2 (l" Fig. 5), but negative for cytoplasmic CD3e. Follicular lymphoma of the duodenum